Relapse, re-infection and mixed infections in tuberculosis disease

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Mixed tuberculosis infections in rural South Vietnam 1 2 Running title : Mixed tuberculosis infections 3 4

1. Pham Ngoc Thach Tuberculosis and Lung Disease Hospital, Ho Chi Minh City, 8 Vietnam** 9 2. National Tuberculosis Reference Laboratory, Centre for Infectious Disease Control 10 (CIb/LIS), National Institute for Public Health and the Environment (RIVM), Bilthoven, 11 The Netherlands 12 3. Tuberculosis and M/XDR-TB Programme, Division of Communicable Diseases, Health 13 Security & Environment, ...

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Mixed tuberculosis infections in rural South Vietnam.

Tuberculosis patients may be infected with or have disease caused by more than one Mycobacterium tuberculosis strain, usually referred to as "mixed infections." These have mainly been observed in settings with a very high tuberculosis incidence and/or high HIV prevalence. We assessed the rate of mixed infections in a population-based study in rural Vietnam, where the prevalences of both HIV and...

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BACKGROUND Recurrence of tuberculosis after treatment makes management difficult and is a key factor for determining treatment efficacy. Two processes can cause recurrence: relapse of the primary infection or re-infection with an exogenous strain. Although re-infection can and does occur, its importance to tuberculosis epidemiology and its biological basis is still debated. We used whole-genome...

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1. Pham Ngoc Thach Tuberculosis and Lung Disease Hospital, Ho Chi Minh City, 8 Vietnam** 9 2. National Tuberculosis Reference Laboratory, Centre for Infectious Disease Control 10 (CIb/LIS), National Institute for Public Health and the Environment (RIVM), Bilthoven, 11 The Netherlands 12 3. Tuberculosis and M/XDR-TB Programme, Division of Communicable Diseases, Health 13 Security & Environment, ...

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ژورنال

عنوان ژورنال: Pathogens and Disease

سال: 2017

ISSN: 2049-632X

DOI: 10.1093/femspd/ftx020